A varicocele is an abnormal dilatation and tortuosity of the pampiniform plexus of veins within the spermatic cord, caused by venous reflux due to incompetent or absent valves in the testicular vein.
Common (≈15% of men, up to 40% in infertile men).
Usually left-sided (due to perpendicular drainage of left testicular vein into left renal vein).
Right-sided or sudden-onset varicocele → suspect retroperitoneal mass/renal tumor compressing IVC or renal vein.
Venous reflux → increased scrotal temperature, hypoxia, and toxin accumulation → impaired spermatogenesis → infertility.
Clinical examination (standing, supine, Valsalva).
Scrotal Doppler ultrasound: gold standard for confirmation (reflux, vein >3 mm).
Semen analysis: to assess infertility.
Renal ultrasound/CT: in isolated right-sided varicocele or sudden-onset in older patient (to rule out secondary cause).
1. Conservative
Asymptomatic, normal semen analysis → observation.
2. Indications for treatment
3. Definitive treatment options